AIDS (stage B2)

A 52 year old male complained over the previous 12 months of dysphagia, loss of taste, and episodes of oral candidiasis which recurred despite symptomatic antimycotic treatment (fluconazole). Oral examination revealed white semiadherent plaques on an erythematous base, bilaterally, on the ventral surface of the tongue (figures 1 and 2). Microscopic examination of material taken from the lesions revealed abundant yeast cells and pseudohyphae. Culture produced confluent growth of a Candida albicans strain belonging to the fuzzy phenotype. The minimum inhibitory concentrations (MICs) to azoles were increased, with break points indicating intermediate sensitivity. Blood tests for underlying immunodeficiency or other systemic disease known to predispose for oral candidiasis were requested.

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