Last update:

    21-May-2008
 

Arch Hellen Med, 25(2), March-April 2008, 209-213

SHORT COMMUNICATION

Miliary tuberculosis in a patient with rheumatoid arthritis following treatment with anti-TNF-�

A.I. PAPAIOANNOU,1 K. KOSTIKAS,1 E. GEROGIANNI,1 M. IOANNOU,2 K.I. GOURGOULIANNIS1
1Department of Respiratory Medicine, University of Thessaly, University Hospital of Larissa,
2Department of Pathology, University of Thessaly, University Hospital of Larissa, Larissa, Greece

Anti-TNF-� agents have been used for the treatment of several autoimmune diseases, including rheumatoid arthritis. Recently observations indicate that treatment with anti-TNF-� agents is associated with increased risk of infectious diseases and especially tuberculosis. A case of a 78-year-old female with rheumatoid arthritis is described who developed miliary tuberculosis after treatment with infliximab. A brief review of the literature is presented.

Key words: Anti-TNF-�, Infliximab, Rheumatoid arthritis, Tuberculosis.


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