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Arch Hellen Med, 33(3), May-June 2016, 399-401


A rare oncological emergency

N. Vallianou,1 E. Geladari,1 P. Chroni,1 K. Trigkidis,1 D. Rontogianni,2 E. Kokkinakis1
1First Department of Internal Medicine, "Evangelismos" General Hospital, Athens
2Department of Pathology, "Evangelismos" General Hospital, Athens, Greece

Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma characterized by an aggressive clinical course with fever, generalized lymphadenopathy, hepatosplenomegaly, anemia, hypergammaglobulinemia and auto-immune-like manifestations. The case is presented of a 60-year-old male patient with AITL who eventually died due to spontaneous tumor lysis syndrome (STL). Vigorous fluid administration with rasburicase and even renal replacement therapy may prove to be life-saving in this clinical setting. STL must be included in the differential diagnosis of acute kidney injury among patients with angioimmunoblastic lymphoma. It may be lethal, as in this patient.

Key words: Acute kidney injury, Angioimmunoblastic lymphoma, Spontaneous tumor lysis syndrome.

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