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Lung angiosarcoma: A rare neoplasm
Dimopoulos G.1, Triggidou R.2, Perros I.1, Mesogitis S.2, Sakellaropoulos A.1, Zetos A.1, Rasidakis A.1
1Respiratory Insufficiency Center,
2Pathology Lab, Athens Chest Hospital, Athens, Greece
SUMMARY: Primary angiosarcomas involving the lung are extremely rare neoplasms characterized by non-specific manifestasions and difficult diagnosis. We report the case of a 33-year old male with dyspnea, nonproductive cough and retrosternal pain. The clinical, laboratory and radiological evaluation of the patient was not diagnostic leading to open lung biopsy performance. Histology and immunohistochemical analysis of surgical specimens confirmed the diagnosis of primary lung angiosarcoma. The detailed examination was negative for secondary metastasis. The patient received chemotherapy but after a follow-up period of one year he presented with brain metastasis. He died 14 months after the confirmation of diagnosis. Pneumon 2005, 18(3):325-328.
Key words: Primary angiosarcoma, rare lung tumors, chemotherapy, prognosis.
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