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Ελληνική Ψυχιατρική Βιβλιογραφία
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Εργασίες εκτός Ελληνικών Ιδρυμάτων - ΜΕΡΟΣ 2
Στο μέρος αυτό οι εργασίες έχουν γίνει από Έλληνες συγγραφείς σε Ιδρύματα του εξωτερικού. Το τμήμα αυτό έχει τις περισσότερες ελλείψεις αφού τις περισσότερες φορές απαιτεί αναζήτηση κάθε συγγραφέα ξεχωριστά
<1>
Accession : Number
Journal Article: 83-27453.
Author :
Lyketsos, Constantine G; Corazzini, Kirsten; Steele, Cynthia.
Institution :
John Hopkins U & Hosp, Dept of Psychiatry & Behavioral Sciences,
Baltimore, MD, US.
Title :
Mania in Alzheimer's disease.
Source :
Journal of Neuropsychiatry & Clinical Neurosciences. Vol 7(3) 350-352, Sum
1995.
Abstract :
Reviewed randomly selected charts of 211 patients to determine the
prevalence of mania in Alzheimer's disease (AD). 134 Ss (mean age 73.2
yrs) were diagnosed with AD. 77 Ss (mean age 73.1 yrs) had dementia, but
did not meet the criteria for AD. The presence of a mania syndrome was
determined through comprehensive clinical examinations and the use of
Diagnostic and Statistical Manual of Mental Disorders-III-Revised
(DSM-III-R). Results revealed that 3 of the 134 Ss developed a manic
episode during the course of their dementia. Case reports of these 3
female patients (aged 66, 72, and 76 yrs) are provided. Only 1 of the 3
cases revealed the presence of mania after the onset of cognitive decline
and could be directly related to AD.
<2>
Accession : Number
Journal Article: 83-12071.
Author :
Lyketsos, Constantine G; Steele, Cynthia.
Institution :
Johns Hopkins Hosp, Baltimore, MD, US.
Title :
The care of patients with dementia.
Source :
Reviews in Clinical Gerontology. Vol 5(2) 179-197, May 1995.
Abstract :
Discusses a treatment plan for elderly dementia patients. Comprehensive
assessment and diagnosis are essential for effective care of the patients.
These help to specify the treatment goals, and develop an effective
treatment plan which can help caregivers in managing these patients.
Elaborate processes are involved in the development of cognitive and
noncognitive complications of dementia. Through some advances, it has been
possible to deal with some elements of a dementia syndrome. The most
successful attempt to treat cognitive impairment in patients with dementia
has been the use of cholinomimetic agents, especially tacrine. Several
intervention strategies are suggested to deal with the noncognitive and
behavioral symptoms, and the psychosocial environment of the patients.
These include dealing with the problem behaviors, depression, delusions
and hallucinations of the patients, and helping the families of the
patients to cope. (ClinPSYC Database Copyright 1996 American Psychological
Assn, all rights reserved).
<3>
Accession : Number
Journal Article: 83-05342.
Author :
Lyketsos, Constantine G; Kraus, Marilyn.
Institution :
Johns Hopkins Hosp, Neuropsychiatry & Memory Group, Baltimore, MD, US.
Title :
The dementia of Gerstmann-Straussler-Scheinker syndrome: Clinical
variability demonstrated by two case reports.
Source :
Journal of Neuropsychiatry & Clinical Neurosciences. Vol 7(2) 239-242, Spr
1995.
Abstract :
Two cases of Gerstmann-Straussler-Scheinker syndrome (GSS) are discussed
in detail, one involving a 31-yr-old woman, the other a 64-yr-old man.
These patients were eventually discovered to be members of the same family
and were referred for genetic counseling, which revealed a human prion
mutation characteristic of GSS. In both cases, dementia was the primary
clinical characteristic throughout the course of the illness, whereas
cerebellar and other subcortical findings were absent or less prominent.
Both patients displayed dysfunction in language, praxis, gnosis, and
memory; prominent personality change with apathy and disinhibition; and no
evidence of ataxia. The young woman was initially diagnosed with
Alzheimer's disease (AD), albeit with an unusually early onset, whereas
the man's case was considered to be Creutzfeldt-Jakob disease.
<4>
Accession : Number
Journal Article: 82-43919.
Author :
Mendelbaum, K; Sevy, S; Souery, D; Papadimitriou, G N; et al.
Institution :
Erasme University Hosp, University Clinics of Brussels, Belgium.
Title :
Manic-depressive illness and linkage reanalysis in the Xq27-Xq28 region of
chromosome X.
Source :
Neuropsychobiology. Vol 31(2) 58-63, Feb 1995.
Abstract :
Inconsistent findings in X linkage studies of manic-depressive illness
(MDI) have been ascribed to the presence of phenotypic uncertainties,
considerable variation in form and severity of MDI, and the likely
presence of phenocopies. To address some of these issues, previous X
linkage data with color blindness, glucose-6-phosphate dehydrogenase
deficiency, and blood coagulation factor IX (F9) markers were reanalyzed
using a narrow and a broad definition of MDI. Data were from 35 families
of bipolar probands informative for X-linked transmission. Results confirm
the X-linked hypothesis for MDI genetic transmission when controlling for
diagnostic variation. The lod score (log of odds ratio) was reduced for a
more conservative definition of the disease, but nevertheless remained
significant. However, conclusive linkage between the MDI gene and the F9
gene in the Xq27 region was not maintained in the series.
<5>
Accession : Number
Journal Article: 82-40954.
Author :
Fava, Giovanni A; Freyberger, Harald J; Bech, Per; Christodoulou,
George; et al.
Institution :
U degli Studi, Bologna, Dipartimento di Psicologia, Italy.
Title :
Diagnostic criteria for use in psychosomatic research.
Source :
Psychotherapy & Psychosomatics. Vol 63(1) 1-8, 1995.
Abstract :
Describes specific psychosomatic syndromes to provide a basis for
psychosomatic medicine and psychotherapy research. The past 2 decades have
resulted in Diagnostic and Statistical Manual of Mental Disorders-IV
(DSM-IV) and International Classification of Diseases (ICD)
classifications of mental disorders. An analysis of their codes reveals
conceptual flaws and clinical inadequacies in the diagnostic criteria. To
remedy these situations, diagnostic criteria of psychosomatic syndromes
are presented for alexithymia, Type A Behavior, abnormal illness behavior,
somatization, irritable mood, and demoralization. Relationships with
current psychiatric nosology are outlined. These patient criteria are to
be used across patient characteristics and can be integrated by
dimensional variables obtained by psychological rating scales and
inventories. Criteria can also be used on a multiaxial approach for
supplemental diagnosis, and psychiatric comorbidity may occur. A field
trial is in preparation to test out these criteria.
<6>
Accession : Number
Journal Article: 82-21378.
Author :
Lyketsos, Constantine G; Nestadt, Gerald; Cwi, Joan; Heithoff, Kim; et
al.
Institution :
Johns Hopkins U, School of Medicine, Dept of Psychiatry & Behavioral
Sciences, Baltimore, MD, US.
Title :
The Life Chart Interview: A standardized method to describe the course of
psychopathology.
Source :
International Journal of Methods in Psychiatric Research. Vol 4(3)
143-155, Oct 1994.
Abstract :
Discusses the development and pilot testing of the Life Chart Interview
(LCI) method, a standardized interview designed to assess the course of
psychopathology as it interdigitates with a person's life history. The
interview method draws from recent developments in autobiographical memory
and life calendar research. The LCI uses age- and calendar-linked personal
landmarks and an interactive chart to describe the time sequence of
psychopathology and life events in parallel. Results from pilot testing of
this interview with 51 community Ss as part of an epidemiologic catchment
area follow-up study are presented. Future directions in the development
and application of the LCI are discussed.
<7>
Accession : Number
Journal Article: 82-21377.
Author :
Lyketsos, Constantine G; Aritzi, Sophia; Lyketsos, George C.
Institution :
Johns Hopkins Hosp, Baltimore, MD, US.
Title :
Effectiveness of office-based psychiatric practice using a structured
diagnostic interview to guide treatment.
Source :
Journal of Nervous & Mental Disease. Vol 182(12) 720-723, Dec 1994.
Abstract :
Assessed the effectiveness of psychiatric treatment in 52 adult patients
seen in a psychiatrist's private practice. Ss' treatment was based on
diagnoses derived from the Composite International Diagnostic Interview
(CIDI). Predetermined diagnosis-specific treatments were then prescribed
and outcome was assessed using the Global Assessment of Functioning Scale.
Agreement between clinical psychiatric and CIDI-based diagnoses was then
assessed. The CIDI diagnosed mood disorders in Ss who had not previously
received such a diagnosis. Additionally, the CIDI was more likely to make
multiple diagnoses and to bring secondary diagnoses into the context of
treatment.
<8>
Accession : Number
Journal Article: 82-10152.
Author :
Lyketsos, Constantine G; Hanson, Anne; Fishman, Marc; McHugh, Paul R;
et al.
Institution :
Johns Hopkins U School of Medicine, Baltimore, MD, US.
Title :
Screening for psychiatric morbidity in a medical outpatient clinic for HIV
infection: The need for a psychiatric presence.
Source :
International Journal of Psychiatry in Medicine. Vol 24(2) 103-113, 1994.
Abstract :
Attempted to ascertain the prevalence and type of psychiatric morbidity
present in HIV-infected patients presenting for the 1st time to a
specialty HIV clinic, and to develop a way of screening for psychiatric
cases in this setting using self-report questionnaires. 50 patients (mean
age 34.6 yrs) who presented for medical care at an HIV clinic
participated. 54% of the Ss were found to suffer from a psychiatric
disorder with an additional 22% suffering from an active substance abuse
disorder. These rates are higher than other clinics report. HIV-infected
patients should be treated for their psychiatric disorder concurrently
with treatment for HIV.
<9>
Accession : Number
Journal Article: 81-25449.
Author :
Lyketsos, Constance G.
Title :
Application of clinical epidemiologic methods to the clinical practice of
psychiatry.
Source :
American Journal of Psychiatry. Vol 151(2) 299-300, Feb 1994.
Abstract :
Comments on D. A. Zarin and F. Earls's (see PA, Vol 80:21667) framework
for diagnostic decision making in psychiatry, noting that its
applicability to everyday clinical practice was not emphasized. While
there is a great need to develop research studies that effectively use the
methods of clinical epidemiology, the inquiry should address questions
directly relevant to clinical care.
<10>
Accession : Number
Literature Review: 81-14338.
Author :
Treisman, Glenn J; Lyketsos, Constantine G; Fishman, Mare; Hanson,
Annette L; et al.
Institution :
Johns Hopkins U School of Medicine, AIDS Psychiatry Service, Baltimore,
MD, US.
Title :
Psychiatric care for patients with HIV infection: The varying
perspectives.
Source :
Psychosomatics. Vol 34(5) 432-439, Sep-Oct 1993.
Abstract :
Reviews the literature on the classification and treatment of psychiatric
morbidity associated with HIV infection. The psychiatric disorders seen in
HIV-infected patients are formulated by using 1 of the following 4
perspectives as treatment guides: (1) the syndromal or disease perspective
(to explain depression, dementia, and psychotic disorders), (2) the
dispositional or personality perspective, (3) the behavioral or addictive
perspective, and (4) the life story perspective. Differentiating disorders
according to these perspectives allows clinical patterns to be identified
and to target treatments.
<11>
Accession : Number
Journal Article: 81-06058.
Author :
Hatzichristou, Chryse; Papadatos, Yiannis.
Institution :
Max Planck Inst for Human Development & Education, Berlin, Germany.
Title :
Juvenile delinquents' perceptions of childhood parental rearing patterns.
Source :
Child Abuse & Neglect. Vol 17(4) 487-494, Jul-Aug 1993.
Abstract :
Examined the extent to which delinquents who reported maltreatment in
childhood could be differentiated from delinquents who did not report
maltreatment. All 287 juvenile delinquents (aged 11-21 yrs) in all
institutions and prisons in Greece were interviewed. Perceived parental
abuse and/or psychological neglect were found to be associated with
various family and social characteristics (e.g., place of birth, parental
marital status, parents' responsiveness to favors, drug use). Specific
parameters connected to the Greek societal and cultural context have also
been identified. (French & Spanish abstracts)
<12>
Accession : Number
Journal Article: 80-33623.
Author :
Ellis, Hadyn D; de Pauw, Karel W; Christodoulou, George N;
Papageorgiou, Lambis; et al.
Institution :
U Wales Coll of Cardiff, School of Psychology, Wales.
Title :
Responses to facial and non-facial stimuli presented tachistoscopically in
either or both visual fields by patients with the Capgras delusion and
paranoid schizophrenics.
Source :
Journal of Neurology, Neurosurgery & Psychiatry. Vol 56(2) 215-219, Feb
1993.
Abstract :
Tested (1) A. B. Joseph's (1986) hypothesis that patients with Capgras
delusion may have problems integrating information between the 2 cortical
hemispheres, and (2) J. Cutting's (1990) ideas linking schizophrenia in
general, and the Capgras delusion in particular, to right hemisphere
dysfunction. Three male patients (aged 22-36 yrs) with the Capgras
delusion and 3 matched controls diagnosed as paranoid schizophrenics were
briefly presented pairs of line-drawn object and photographs of faces
randomly in the left visual field, the right visual field, or bilaterally.
Results are not consistent with a simple prediction from Joseph's
hypothesis but they are in partial agreement with Cutting's theory.
Results point to the likely advantages to be derived from adopting a
cognitive neuropsychiatric approach to studying Capgras delusion.
<13>
Accession : Number
Journal Article: 80-22376.
Author :
Lyketsos, Constantine G; Stoline, Anne M; Longstreet, Peter; Ranen,
Neal G; et al.
Institution :
Johns Hopkins U School of Medicine, Baltimore, MD, US.
Title :
Mania in temporal lobe epilepsy.
Source :
Neuropsychiatry Neuropsychology & Behavioral Neurology. Vol 6(1) 19-25,
Jan 1993.
Abstract :
Conducted a retrospective chart review of 25 patients (aged 19-53 yrs)
with temporal lobe epilepsy (TLE) and of 50 patient controls (aged 17-102
yrs) without TLE to determine the incidence of mania. Results showed a
higher than expected rate of mania in patients with TLE. These are
contrasted with results of a literature review, which confirm that
previous reports of mania in these patients are few. The implications of
these results with regard to the assessment and treatment of psychiatric
syndromes affecting patients with TLE are discussed. Treatment with Li did
not cause worsening of seizures in patients with TLE and mania. Four cases
are briefly presented.
<14>
Accession : Number
Symposium & Conference Presentations: 80-22283.
Author :
Lyketsos, Constantine G; Hanson, Annette L; Fishman, Mark; Rosenblatt,
Adam; et al.
Institution :
Johns Hopkins U & Hosp, Baltimore, MD, US.
Title :
Manic syndrome early and late in the course of HIV. Annual Meeting of
Psychosomatic Medicine (1992, San Diego, Californina).
Source :
American Journal of Psychiatry. Vol 150(2) 326-327, Feb 1993.
Abstract :
In a chart review at a hospital's infectious disease AIDS clinic, manic
syndromes affected 8% of patients who had AIDS. Of the 14 patients with
manic episodes, those without a family or personal history of mood
disorder presented later in the course of HIV infection and had a higher
prevalence of comorbid dementia.
<15>
Accession : Number
Journal Article: 80-03002.
Author :
Bouras, N; Webb, Y; Clifford, P; Papadatos, Y; et al.
Institution :
U London United Medical & Dental Schools of Guy's & St Thomas's Hosps,
Guy's Hospital Div of Psychiatry, England.
Title :
A needs survey among patients in Leros Asylum.
Source :
British Journal of Psychiatry. Vol 161 75-79, Jul 1992.
Abstract :
A survey of the characteristics and needs for care among 1,179 patient
residents (aged 14-89 yrs) in Leros State Mental Hospital in Greece found
that most Ss had no outside friends or relatives, and most were unable to
perform basic daily skills. Ss shared many basic characteristics with a
large sample of the long-stay population in the UK, and 25% were thought
to be able to live independently.
<16>
Accession : Number
Journal Article: 80-01719.
Author :
Ellis, H; de Pauw, K; Christodoulou, G N; Luaute, J-P; et al.
Institution :
U Wales Coll of Cardiff, School of Psychology, Wales.
Title :
Recognition memory in psychotic patients.
Source :
Behavioural Neurology. Vol 5(1) 23-26, Mar 1992.
Abstract :
Presents preliminary data from experiments in which the Recognition Memory
Test was given to patients with misidentification delusions, including the
Capgras type, and to other psychotic patients. Results show a profound
impairment on face recognition for most groups, especially those with the
Capgras delusion. It was rare to find a patient whose score on the word
test was anything but normal. Results are in accord with J. Cutting's
(1990) theory that schizophrenia is largely the result of right hemisphere
dysfunction.
<17>
Accession : Number
Journal Article: 79-28429.
Author :
Lyketsos, C G.
Title :
Successful treatment of bowel obsessions with nortriptyline.
Source :
American Journal of Psychiatry. Vol 149(4) 573, Apr 1992.
Abstract :
Reports the case of a 65-yr-old man preoccupied with the worry that he
would be flatulent in public. His worry led to extreme social withdrawal
and the loss of a successful business career. After unsuccessful treatment
with a number of drugs, his symptoms responded to nortriptyline. This case
raises questions concerning the classification and treatment of "bowel
obsessions."
<18>
Accession : Number
Journal Article: 76-26170.
Author :
Sevy, Serge; Papadimitriou, Georges N; Surmont, Daisy W; Goldman,
Serge; et al.
Institution :
Free U of Brussels, Erasme Hosp,, Belgium.
Title :
Noradrenergic function in generalized anxiety disorder, major depressive
disorder, and healthy subjects.
Source :
Biological Psychiatry. Vol 25(2) 141-152, Jan 1989.
Abstract :
Measured plasma norepinephrine (NE), free 3-methoxy-4-hydroxyphenethylene
glycol (MHPG), and binding of tritiated yohimbine to platelet membranes in
14 patients (aged 20-65 yrs) with generalized anxiety disorder (GAD), 14
patients (aged 22-61 yrs) with unipolar major depressive disorder (MDD),
and 14 normal Ss (aged 22-65 yrs). Plasma NE and MHPG levels were
increased and the number of alpha-sub-2-adrenoreceptors (B-sub(max)) was
decreased in GAD Ss compared with MDD and normal Ss. Plasma NE and MHPG
were significantly correlated in MDD Ss and tended toward a significant
positive correlation in GAD Ss. Plasma MHPG and affinity of binding
platelet alpha-sub-2-adrenoreceptors (K-sub(d)) were significantly
correlated in normal Ss.
<19>
Accession : Number
Journal Article: 76-22726.
Author :
Linkowski, Paul; de Maertelaer, Viviane; Delarbre, Carine;
Papadimitriou, George; et al.
Institution :
Hopital Erasme, Brussels, Belgium.
Title :
Familial factors in suicidal behavior.
Source :
International Journal of Family Psychiatry. Vol 9(2) 123-133, 1988.
Abstract :
Investigated suicidal behavior in 453 female and 260 male major
depressives (aged 16-86 yrs). Presence of suicide among relatives and
information about the method of suicide used were obtained from all
available sources. Analysis of data showed that a family history of
suicidal behavior (mainly by violent means) was unequivocally associated
with an increase in the frequency of such behavior in depressive women
(more often in bipolar than in unipolar Ss). In depressed men, the
presence of violent or nonviolent suicidal behavior was not significantly
affected by the polarity of depression.
<20>
Accession : Number
Journal Article: 76-19963.
Author :
Kales, Anthony; Soldatos, Constantin R; Bixler, Edward O; Kales, Joyce
D; et al.
Institution :
Pennsylvania State University Coll of Medicine, Milton S. Hershey Medical
Ctr, Hershey, US.
Title :
Diazepam: Effects on sleep and withdrawal phenomena.
Source :
Journal of Clinical Psychopharmacology. Vol 8(5) 340-346, Oct 1988.
Abstract :
Assessed the efficacy and side effects associated with the initial and
short-term administration of diazepam at bedtime in 6 insomniac patients
(aged 26-61 yrs). The presence of withdrawal sleep disturbance during the
week following abrupt drug withdrawal was also assessed. Findings contrast
with those for rapidly eliminated benzodiazepine drugs.
<21>
Accession : Number
Journal Article: 75-27142.
Author :
Vela-Bueno, Antonio; Soldatos, Constantin R; Julius, Demetrios A.
Institution :
U Autonoma de Madrid, Spain.
Title :
Parasomnias: Sleepwalking, night terrors, and nightmares. Special Issue:
Sleep disorders.
Source :
Psychiatric Annals. Vol 17(7) 465-469, Jul 1987.
Abstract :
Discusses the evaluation and treatment of parasomnias. Characteristics of
parasomnias are described, along with causative factors and differential
diagnosis. Sleepwalking and night terrors are considered to be disorders
involving impaired arousal, occur during slow-wave sleep, and are more
common in children than adults. Nightmares occur during REM sleep, and
recall is usually more vivid than sleepwalking or night terrors. Suggested
treatment for sleepwalking or night terrors in children involves
protection from self-injury. Treatment for nightmares involves
reassurances that nightmares are a normal part of childhood and will be
outgrown. It is noted that parasomnias in adults usually reflect
underlying psychopathology.
<22>
Accession : Number
Journal Article: 75-20627.
Author :
Kales, Anthony; Bixler, E O; Soldatos, Constantine R; Cadieux, R J; et
al.
Institution :
Pennsylvania State University Coll of Medicine, Milton S. Hershey Medical
Ctr, Hershey, US.
Title :
Narcolepsy/cataplexy: IV. Diagnostic value of daytime nap recordings.
Source :
Acta Neurologica Scandinavica. Vol 75(4) 223-230, Apr 1987.
Abstract :
Compared sleep patterns during daytime naps in 50 narcoleptic patients
(mean age 42.6 yrs) and 50 age-matched controls. A sleep-onset REM period
in either of 2 daytime naps had a higher diagnostic sensitivity for
narcolepsy than an abnormally shortened sleep latency, although the 2
latencies had similar specificity. Separately, the latencies increased
overall sensitivity and decreased specificity. The use of these measures
for clinical diagnosis of narcolepsy is discussed.
<23>
Accession : Number
Journal Article: 75-16999.
Author :
Dencker, Sven J; Boulougouris, John; Greist, John H.
Institution :
Lillhagen Hosp, Dept II, Hisings Backa, Sweden.
Title :
Research values and priorities rated by psychiatric patients.
Source :
Acta Psychiatrica Scandinavica. Vol 74(331, Suppl) 114-119, 1986.
Abstract :
Compared the social values and priorities of a heterogenous group of 35
adult psychiatric patients (from Greece, Sweden, Scotland, and the US)
with 240 adult nonpatients. The hypothesis that the research values and
priorities of patients would differ from those of the nonpatients was
supported by the statistical analysis. Most significant group differences
were found for the categories of mental and physical health followed by
work, education, nonmaterial, services, security, and other knowledge.
<24>
Accession : Number
Journal Article: 70-13284.
Author :
Kales, Anthony; Soldatos, Constantin R; Bixler, Edward O; Kales, Joyce
D.
Institution :
Pennsylvania State U, Coll of Medicine Sleep Research & Treatment Ctr,
Hershey.
Title :
Early morning insomnia with rapidly eliminated benzodiazepines.
Source :
Science. Vol 220(4592) 95-97, Apr 1983.
Abstract :
Conducted 6 sleep laboratory evaluations of 4 benzodiazepine hypnotic
drugs--midazolam, triazolam, flurazepam, and quazepam--using 21 Ss. Early
morning insomnia, a significant increase in wakefulness during the final
hours of drug nights, occurred after 1 or 2 wks of nightly administration
of benzodiazepine hypnotics with short elimination half-lives, when
tolerance had begun to develop. Early morning insomnia may be a variant of
rebound insomnia and therefore specific to benzodiazepines or it may occur
with any rapidly eliminated sedative-hypnotic agent.
<25>
Accession : Number
Journal Article: 70-06274.
Author :
Nestoros, Joannis N; et al.
Institution :
Douglas Hosp Research Ctr, Verdun, Canada.
Title :
Diazepam in high doses is effective in schizophrenia.
Source :
Progress in Neuro-Psychopharmacology & Biological Psychiatry. Vol 6(4-6)
513-516, 1982.
Abstract :
Administered up to 400 mg diazepam/day to 6 paranoid schizophrenics while
6 others received placebos. The effects of treatment were assessed by 6
scales, including the Brief Psychiatric Rating Scale. Within a few hours
to a few days, both positive (such as auditory hallucinations and
persecutory delusions) and negative (such as emotional withdrawal and
blunted affect) schizophrenic symptoms were dramatically eliminated in 5
Ss receiving diazepam. (15 ref)
<26>
Accession : Number
Journal Article: 70-06272.
Author :
Nair, N Vasavan; Bloom, David M; Nestoros, Joannis N.
Institution :
Douglas Hosp Research Ctr, Verdun, Canada.
Title :
Cholecystokinin appears to have antipsychotic properties.
Source :
Progress in Neuro-Psychopharmacology & Biological Psychiatry. Vol 6(4-6)
509-512, 1982.
Abstract :
Studied the effects of cholecystokinin, a neuromodulator of dopaminergic
neurotransmission, in 6 chronic paranoid schizophrenics (aged 24-49 yrs)
using the Brief Psychiatric Rating Scale and the Schizophrenia subscale of
the Present State Examination. An ANOVA revealed statistically significant
improvements in all test factors within 1 day. (26 ref)
<27>
Accession : Number
Journal Article: 70-05231.
Author :
Nestoros, Joannis N.
Institution :
Douglas Hosp Research Ctr, Verdun, Canada.
Title :
Benzodiazepine and GABA receptors are functionally related: Further
electrophysiological evidence in vivo.
Source :
Progress in Neuro-Psychopharmacology & Biological Psychiatry. Vol 6(4-6)
417-420, 1982.
Abstract :
Tested the effects of 5 benzodiazepines (flurazepam, chlordiazepoxide,
midazolam maleate, medazepam, and clozapine) on GABA-mediated electrically
evoked cortical inhibition in 14 cats. When tested with equal
iontophoretic doses in 11 neurons, the degree of potentiation of
electrically evoked cortical inhibition produced by the benzodiazepines
correlated significantly with the logarithm of the Ki values of these
drugs for inhibiting specific -sup-3H-diazepam binding to rat brain
membranes. Results support the hypothesis that GABAergic mechanisms have a
special role in the neurophysiology of anxiety. (21 ref)
<28>
Accession : Number
Journal Article: 69-06005.
Author :
Nestoros, Joannis N; Demers-Desrosiers, Louise A; Dalicandro, Lucy A.
Institution :
Douglas Hosp Research Ctr, Montreal, Canada.
Title :
Levels of anxiety and depression in spinal cord-injured patients.
Source :
Psychosomatics. Vol 23(8) 823-830, Aug 1982.
Abstract :
Tested the hypothesis that the experience of anxiety or depression
correlates with the degree of sensory input. The levels of anxiety and
depression in 19 17-61 yr old quadriplegic and 16 18-60 yr old paraplegic
patients were compared by administering the Self-Rating Depression Scale.
Results show that the majority of Ss scored within the normal range.
Quadriplegic Ss were not significantly more depressed or anxious than
paraplegic Ss, and levels of spinal cord lesions were not associated with
any significant differences in scores. Results suggest that the level of
sensory input is unlikely to play a dominant role in anxiety and
depression. (10 ref)
<29>
Accession : Number
Journal Article: 69-03941.
Author :
Kales, Joyce D; Cadieux, Roger J; Soldatos, Constantin R; Kales,
Anthony.
Institution :
Pennsylvania State University Coll of Medicine, Sleep Research & Treatment
Ctr, Hershey.
Title :
Psychotherapy with night-terror patients.
Source :
American Journal of Psychotherapy. Vol 36(3) 399-407, Jul 1982.
Abstract :
Investigated the effectiveness of psychotherapy in treating 3 male
night-terror patients (aged 22, 26, and 27 yrs). Night terrors were
eliminated or drastically reduced in 2 Ss who completed psychotherapy. The
3rd S discontinued therapy and showed no improvement. (13 ref)
<30>
Accession : Number
Literature Review: 67-12249.
Author :
Nestoros, J N; Lehmann, H E; Ban, Thomas T.
Institution :
Douglas Hosp, Montreal, Canada.
Title :
Sexual behavior of the male schizophrenic: The impact of illness and
medications.
Source :
Archives of Sexual Behavior. Vol 10(5) 421-442, Oct 1981.
Abstract :
The literature concerning the impact of schizophrenic illness and
neuroleptic drugs on male sexual behavior is reviewed in the light of the
interactions among psychiatric illness, neuroleptic drugs, and the
hormones and neurotransmitters known to play a role in male sexual
behavior. The effect of the schizophrenic illness on male sexual behavior
is unclear, but there are some indications that chronic, severe
schizophrenia may exert detrimental effects on many aspects of male sexual
behavior. As for neuroleptic drugs, evidence suggests that they have many
detrimental effects on male sexual behavior. Nevertheless, since the
introduction of these drugs, the reproductive rates of male schizophrenics
have increased. The multiplicity of factors involved in the sexual
behavior of the schizophrenic patient is emphasized. It is concluded that
the sexual behavior of the male schizophrenic provides an important forum
for studying the interaction between psychological, sociological, and
biochemical-pharmacological factors that determine sexual behavior. (5 p
ref)
<31>
Accession : Number
Journal Article: 66-03942.
Author :
Soldatos, Constantin R; Kales, Anthony; Kales, Joyce D.
Institution :
Pennsylvania State U School of Medicine, Sleep Research & Treatment Ctr,
Hershey.
Title :
Management of insomnia.
Source :
Annual Review of Medicine. Vol 30 301-312, 1979.
Abstract :
Presents clinical and sleep laboratory findings regarding prevalence of
insomnia and demographic variables associated with insomniac patients.
Causative factors, both physical and emotional, are noted with emphasis
given to the psychological problems associated with insomnia. Assessment
procedures are outlined. Nonpharmacologic treatments such as biofeedback
and relaxation are discussed, as is chemotherapy for sleep disturbances
that accompany depression and schizophrenia. (29 ref)
<32>
Accession : Number
Journal Article: 66-00915.
Author :
Nestoros, J N.
Institution :
McGill U, Montreal, Canada.
Title :
Ethanol specifically potentiates GABA-mediated neurotransmission in feline
cerebral cortex.
Source :
Science. Vol 209(4457) 708-710, Aug 1980.
Abstract :
Reports that ethanol (ethyl alcohol) potentiated the inhibition of
cortical neurons by gamma-aminobutyric acid (GABA) in cats. This effect is
specific, since ethanol does not potentiate inhibition by glycine,
serotonin, or dopamine. These results have implications for alcoholism
because (1) GABA mediates anxiolytic mechanisms, and (2) anxiety is
implicated in the etiology of alcoholism. (33 ref)
<33>
Accession : Number
Journal Article: 65-07557.
Author :
Soldatos, Constantin R; et al.
Institution :
Pennsylvania State U, Sleep Research & Treatment Ctr, Hershey.
Title :
Cigarette smoking associated with sleep difficulty.
Source :
Science. Vol 207(4430) 551-553, Feb 1980.
Abstract :
Results from 2 studies with 100 Ss (approximate mean age, 35 yrs) indicate
that smokers experienced greater sleep difficulty than age- and
sex-matched nonsmoker controls. The 2 groups did not differ in personality
patterns (MMPI) or drug consumption. Also, sleep patterns significantly
improved in 8 chronic smokers when they abstained from cigarette smoking.
Findings are consistent with reports on the stimulant effects of nicotine.
(17 ref)
<34>
Accession : Number
Journal Article: 65-01828.
Author :
Charney, Dennis S; Kales, Anthony; Soldatos, Constantin R; Nelson, J
Craig.
Institution :
Yale U School of Medicine.
Title :
Somnambulistic-like episodes secondary to combined lithium-neuroleptic
treatment.
Source :
British Journal of Psychiatry. Vol 135 418-424, Nov 1979.
Abstract :
10 15-49 yr old psychiatric patients undergoing combined
lithium-neuroleptic treatment exhibited somnambulisticlike episodes. These
episodes were differentiated from nocturnal wanderings and epileptic
attacks during sleep in that they occurred 2-3 hrs after sleep onset and
were characterized by Ss appearing confused and walking about in a quiet,
detached, and clumsy manner. Generally, there was amnesia for the event.
Since sleepwalking occurs out of slow-wave sleep, the increase in
slow-wave sleep induced by lithium and certain neuroleptics may represent
a neurophysiological mechanism responsible for these Ss' behavior. The
occurrence of grand mal seizures in 2 Ss was probably unrelated to the
episodes. However, persistence of the latter appears to be associated with
drug-induced EEG irregularity. (34 ref)
<35>
Accession : Number
Journal Article: 64-08141.
Author :
Blackburn, Ivy M; Lyketsos, G; Tsiantis, John.
Institution :
MRC Brain Metabolism Unit, Thomas Clouston Clinic, Edinburgh, Scotland.
Title :
The temporal relationship between hostility and depressed mood.
Source :
British Journal of Social & Clinical Psychology. Vol 18(2) 227-235, Jun
1979.
Abstract :
Studied 19 depressed inpatients (mean age 50.6 yrs) in a follow-up design
for 8 wks or until discharge using 3 depression scales (Hamilton Rating
Scale for Depression, Beck Depression Inventory, and the Systematic
Nursing Observation of Psychopathology) and the Hostility and Direction of
Hostility Questionnaire. It was hypothesized within a cognitive theory of
depression that, self-rated hostility being a measure of negative thoughts
and attitudes, changes in hostility would precede mood changes. The
hypothesis was confirmed by the cross-correlations between nurses' mood
ratings and intropunitiveness and direction of hostility. The
cross-correlations with Beck and Hamilton scales supported the hypothesis
at a nonsignificant level. (29 ref)
<36>
Accession : Number
Literature Review: 63-12503.
Author :
Nestoros, J N; Ananth, J V; Caille, G.
Institution :
McGill U, Allan Memorial Inst of Psychiatry, Montreal, Canada.
Title :
A patient with resistance to neuroleptics: A genetic trait?.
Source :
Psychiatric Journal of the University of Ottawa. Vol 3(4) 243-244, Dec
1978.
Abstract :
Presents the case of a schizophrenic Eskimo who showed no therapeutic
response and no side effects despite very high plasma levels of
chlorpromazine. It is suggested that resistance to neuroleptics may be
genetically determined and that nonresponders may have high plasma levels
associated with negligible amounts of metabolites. (7 ref)
<37>
Accession : Number
Journal Article: 63-01639.
Author :
Nestoros, J N; Lehmann, H E; Ban, Thomas A.
Institution :
McGill U, Montreal, Canada.
Title :
Butaclamol in the treatment of schizophrenia: A standard-controlled
clinical trial.
Source :
International Pharmacopsychiatry. Vol 13(3) 138-150, 1978.
Abstract :
Conducted a 16-wk controlled double-blind study to compare the efficacy of
butaclamol with that of fluphenazine in the treatment of 24 newly admitted
schizophrenic patients (mean age 30.1 yrs). Statistically significant
improvement occurred in the entire sample in total scores on the Brief
Psychiatric Rating Scale (BPRS) and the Psychopathological Assessment
Scale (PAS)--in the activation, anergia, thought disturbance, and
hostile/suspiciousness factor scores of the BPRS and in the scores of 9 of
the 12 factors of the PAS. There were no statistically significant
differences between the scores of the 2 treatment groups on the total or
factor scores of either scale during the course of the clinical trial. The
most frequent adverse effects in the butaclamol group were rigidity,
akathisia, and excitement/agitation. The most frequent adverse effects in
the fluphenazine group were insomnia, decreased motor activity, and
tremor. It is concluded that butaclamol exerts potent neuroleptic effects
on schizophrenic patients. (14 ref)
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Στείλτε μας τα σχόλιά σας: PsychoMednet Hellas
Τελευταία ενημέρωση: 17 Φεβρουαρίου 1997
