RESISTANCE TO QUINOLONES

A. Percent resistance to ciprofloxacin
Multicentre results
Data from 14 Hospitals
Only first isolate per patient is included

	Kl. pneumoniae			Enterobacter spp			Ps. Aeruginosa			A. baumanii			S. aureus
	No	%R	%I	No	%R	%I	No	%R	%I	No	%R	%I	No	%R	%I
WARDS	496	12,3	1,8	521	16,3	2,7	993	27,8	3,4	299	76,6	2,0	688	27,0	2,2
I.C.U	149	55,7	7,4	96	39,6	7,3	421	66,5	2,9	238	92,4	0,9	273	68,9	1,9
OUTPATIENTS	66	3,3	0,0	63	3,3	1,7	95	11,6	2,1	2	0	0	110	5,6	2,6

B. Percent resistance to ciprofloxacin by hospital (only wards are included).
Data from 9 hospitals are included.

C. Resistance phenotypes of the ciprofloxacin resistant clinical isolates

K. pneumoniae Enterobacter spp P. aeruginosa A. baumanii S. aureus

No of isolates: 68 No of isolates : 74 No of isolates:217 No of isolates:339 No of isolates 413

Phenotype % Phenotype % Phenotype % Phenotype % Phenotype %

ID1G2X* 30,9 D 2X 36,5 PD1G2N 24 DG2 26 OEXG 44,6

ID1G2XN 16,2 DG2X 27 PD1G2 11,5 SDG2 13,9 OE G 32,9

ID1 2X 16,2 D X 9,5 P 1G2 11,5 SDG 12,1 OE 8,2

D1G2X 7,4 DG X 8,1 P 1G2N 10,6 SD 2 9,7 O XG 5,3

D1 2X 7,4 D1G2N 7,4 D 2 8,8

DG2N 8

DG 8

Other 22,1 Other 18,9 Other 35 Other 13,6 Other 9

ALL 100 ALL 100 ALL 100 ALL 100 ALL 100

*I: Cefoxitin, D: Ceftazidime, 1: Aztreonam, G: Gentamicin
2: Netilmicin X: Cotrimoxazole N: Imipenem, P: Piperacillin
S: Amp/Sulbactam O: Oxaciline E: Erythromycin

K. pneumoniae		Enterobacter spp		P. aeruginosa		A. baumanii		S. aureus
No of isolates: 68		No of isolates : 74		No of isolates:217		No of isolates:339		No of isolates 413
Phenotype	%	Phenotype	%	Phenotype	%	Phenotype	%	Phenotype	%

ID1G2X*	30,9	D 2X	36,5	PD1G2N	24	DG2	26	OEXG	44,6
ID1G2XN	16,2	DG2X	27	PD1G2	11,5	SDG2	13,9	OE G	32,9
ID1 2X	16,2	D X	9,5	P 1G2	11,5	SDG	12,1	OE	8,2
D1G2X	7,4	DG X	8,1	P 1G2N	10,6	SD 2	9,7	O XG	5,3
D1 2X	7,4			D1G2N	7,4	D 2	8,8
						DG2N	8
						DG	8

Other	22,1	Other	18,9	Other	35	Other	13,6	Other	9

ALL	100	ALL	100	ALL	100	ALL	100	ALL	100