��

��. ��:

30-Jul-2000

�� , 16(4), ��-�� 1999, 391-393

��

�� Coxsackie-B4

�. ��, �. ��, �. ��, �. ��,
�. ��, �. ��, �. ��
�� , �� , ��

�� : ��, Coxsackie

�� Coxsackie (RNA ��) �� , �� Echo �� . �� Coxsackie �� , �� . � �� , �� . � �� , ��, �� . �� 23 �� 6 �� . � �� . ��, �� DNA-�� .

�� Coxsackie �� . �� , �� .

� �� Coxsackie �� . ��, �� .¹

� �� , �� Coxsackie-�4.

� �� .

�� 

�� 47 ��, � �� 10 �� 39,5 �C �� . �� . �� 3 �� , �� . �� , �� (�� 10 mg/dL), �� : SGOT 38 U/L �� SGPT 114 U/L. �� , �� .

�� , �� . �� : �� 39,5 �C, �� 100/min, �� 100/80 mmHg, �� . �� 3 cm �� , �� .

�� . �� : Ht: 29,3%, �� 12.600/mm³ (�� 93%, �� 4%), ��: 302.000/mm³, ��: 3,7%, ��: 85 mm. ��: 138 mg/dL, ��: 14 mg/dL, ��: 0,9 mg/dL, SGOT: 60 U/L, �� : 10,3 mg/dL, ��: 6 mg/dL, �� : 6,2 g/L, ��: 3,6 g/L, �� : 14 sec (��: 13 sec), ��: 128 mg/dL, ��: 161 mg/dL, LDH: 242 U/L, CPK: 72 U/L, �� : 3,9 mg/dL, ��: 13 U/L, ��: 8,9 mg/dL. �� : ��: 46,3%, �₁-��: 8,4%, �₂: 18,9%, �: 10%, �: 16,9%. �� . �� Widal-Wright: ��. �� Laveran: ��. �� , ��, ��: ��. �� , �, C, ��: ��. �� : ��. �� IgM �� Coxsackie: �1: 1/32, B2: <1/8, �3:1/8, �4: 1/1024, �5: <1/8 (�� ). �� -��: ��.

�� : �� 169 cm, �� . �� .�.

�� : �� , �� 2�1 cm. �� 3�2,5 cm. ��: �.�.

�� : �� , �� . �� . �� . �� . � �� .

� �� , �� . �� 10�� . � �� :

Ht: 29,2%, ��: 13.700/mm³, ��: 488.000/mm³, ��: ��: 2,5 mg/dL, ��: 1,5 mg/dL, SGOT: 60 U/L, SGPT: 81 U/L, �GT: 150 U/L, �� : 350 U/L.

�� 15�� : 1,3, mg/dL, ��: 0,3 mg/dL, SGOT: 43 U/L, SGPT: 50 U/L, �GT: 70 U/L, �� : 170 U/L. �� 2 �� IgM �� Coxsackie-�4 (1/1024).

�� 6 ��, �� Coxsackie-B4 �� : �� IgM: �� 1/152 �� IgG: �� 1/256.

��

� �� , � �� , �� , ��, ��, �� , ��, �� , �� . �� . �� , �� . �� .

�� , � �� , �� .

�� , �� , �� , �� . ��, �� , �� , �, C, �� CMV, �bstein-Barr �.��., �� , ��, ��, ��, ��. � �� . ��, �� Coxsackie �� IgM �� Coxsackie-�4, �� . � �� , �� Coxsackie �� . �� Coxsackie-B4 �� 2 �� ,⁶ �� .

�� . ��, �� , �� . � �� , �� Coxsackie¹ (�� 1, 2). � ��, �� , �� . �� , � �� .

� �� (�� ) �� . � �� , �� , �� GT, �� . �� . �� 15�� . � �� Coxsackie, �� .

� �� , �� , �� , �� . � �� (Ht: 29,3%) �� (��: 3,7%, �� : 4,3 mg/dL) �� .

� �� , �� ,³ �� . �� , ��' �� .

�� , � ��, �� , �� 2 �� . � �� IgM �� IgG �� Coxsackie. ��, �� IgM �� Coxsackie-B4 �� 2 �� . ��, �� IgG �� Coxsackie-�4 �� 4 �� . �� . �� 4 �� .

� �� . �� Coxsackie-B4 �� .

��

SIMSON IW, GEAR JH. Enteroviruses. In: MacSween RN, Anthony P, Scheuer P (eds) Pathology of the liver. Churchill Livingstone, London, 1987:229
RAY G. Enteroviruses and reoviruses. In: Harrison�s Principles of Internal Medicine. 13th ed. McGraw Hill, 1994:821�824
MODLIN FJ. Coxsackieviruses, echoviruses and newer enteroviru ses. In: Mandel, Douglas, Bennets (eds) Principles and Practice of Infectious Diseases. Churchill Livingstone Inc, New York, 1995: 1620�1629
SHERLOCK S, DOOLEY J. Diseases of the Liver and Biliary System. 9th ed. Blackwell, London, 1993:291
GRIST NR, BELL EJ. Enteroviruses. In: Weatherall DJ, Ledingham JGG, Warell DA (eds) Oxford Textbook of Medicine. 3rd ed. Oxford Medical Publ, 1996, 1:383�390
KIBRICK J. Coxsackie B4 infection in neonatals. Pediat 1958, 22:857
RIZZETO M. Enteroviruses. In: McIntyre M, Benhamou JP, Bicher J, Rizzeto M, Rodes J (eds) Oxford Textbook of Clinical Hepatology. Oxford, Oxford University Press, 1991:636�637

� 2000, �� c��