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28-Jul-2000

�� , 16(6), ��-�� 1999, 580�589

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�� bcl-2 �� bax ��
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�� bcl-2 �� bax �� . �� bcl-2 �� bax �� 81 �� .
��-�� 60 �� 19 ��, 16 ��, 10 �� -�� 15 �� . �� 21 �� . �� bcl-2 �� bax �� Histoscore (HSC), �� (1�4) �� (1�3). �� in situ �� DNA (ISEL) �� (��).
�� bcl-2 �� 58% �� , �� 32 (53,5%) �� 15 (71,5%) �� . � �� bax �� 65 (80%) �� , �� 50 (83,5%) �� 15 (71,5%) �� . �� bcl-2 HSC �� (4,95) �� ,�� (2,76) �� (P=0,02). �� bax HSC, �� (5,91) �� (5,58) ��. ��, 45 �� 81 (55,5%) �� ISEL. �� (5,7%) �� ,�� (1,92%) �� (P=0,03). �� (6,81%), �� (5,57%), �� (5,51%) �� -�� (4,59%) ��. �� bcl-2 �� (P=0,02). ��, � �� bax.
�� , �� . � �� bcl-2 �� bax ��, ��, �� . �� bcl-2/bax �� .

�� : �� , ��, bax, bcl-2, ��.